Item 5.02. Departure of Directors or Principal Officers; Election of Directors;

           Appointment of Certain Officers; Compensatory Arrangements of Certain
           Officers.

On January 14, 2022 - Lode-Star Mining Inc. ("Lode-Star", the "Company" or "We") (OTCQB:LSMG) is pleased to announce that in connection with the acquisition of Sapir Pharmaceuticals, Inc (announced December 30, 2021) it has appointed Mr. Samuel Sternheim as a member of the Board of Directors effective January 14, 2022. Mr. Sternheim will also be assuming the roles of Corporate Secretary, Chief Financial Officer and Treasurer.

Mr. Sternheim started his career as a financial advisor working with high net worth individuals and advising on wealth management. He then actively managed multiple businesses while working for a family office in NY. He is a director of Sapir Pharmaceuticals, and has been CFO of Sapir since 2015, where he has overseen fundraising, numerous acquisitions and licensing ventures globally.

ITEM 9.01 FINANCIAL STATEMENTS AND EXHIBITS






(d)  Exhibits



Number   Exhibit

  99.1     Press Release dated January 11, 2022

104      Cover Page Interactive Data File (embedded within the Inline XBRL
         document).

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