On December 19, 2018, Robert S. Langer, Sc.D. notified Kala Pharmaceuticals, Inc. of his decision to resign as a member of the Board of Directors of the Company, effective immediately. With the resignation, Dr. Langer also resigned as a member of the Company’s Nominating and Corporate Governance Committee. There were no disagreements between Dr. Langer and the Company or any officer or director of the Company which led to Dr. Langer’s resignation.