The board of directors of HBM Holdings Limited announces that Mr. Xiaoxiang Chen ("Mr. Chen") has tendered his resignation as an executive Director with effect from 5 May 2022 for the reason of seeking other opportunities in his career development. Following Mr. Chen's resignation, Dr. Humphrey Gardner, the Chief Medical Officer of the Company, will take over Mr. Chen's responsibilities in leading the global clinical development of the Company. The Board announce that with effect from the date of this announcement, Dr. Yiping Rong ("Dr. Rong") has been appointed as an executive Director.

Dr. Rong was an associate scientist at Shanghai Biochip Co. Ltd. between June 2002 and June 2003.