The 87-year-old pontiff, who has had a number of health issues recently, had cancelled appointments on Saturday and on Monday due to what the Vatican called a mild flu.
On Sunday, however, he addressed crowds in St Peter's Square as normal, to deliver his Angelus message.
"Dear brothers and sisters, I still have a bit of a cold", Francis said, announcing that someone else would read his catechesis on envy and vainglory, two of the seven deadly sins.
In December, the pope was forced to cancel a planned trip to a COP28 climate meeting in Dubai because of the effects of influenza and lung inflammation.
In January, he was unable to complete a speech owing to "a touch of bronchitis". Later in the month he said he was doing better despite "some aches and pains".
As a young man in his native Argentina, Francis had part of a lung removed.
The pope also has difficulty walking, and regularly uses a wheelchair or a cane. On Wednesday, he arrived at his indoor audience in a wheelchair.
(Reporting by Alvise Armellini, editing by Miral Fahmy)
