Valuation: Denali Therapeutics Inc.

Market Cap 3.2B 16.7B 2.84B 2.65B 2.41B 4.55B 308B 4.6B 32.11B 12.44B 157B 12B 11.74B 505B P/E 2026 *
-8.65x
P/E 2027 * -8.72x
Enterprise Value 2.49B 13B 2.21B 2.06B 1.88B 3.54B 240B 3.58B 24.99B 9.69B 122B 9.34B 9.14B 393B EV / Sales 2026 *
49.2x
EV / Sales 2027 * 18.9x
Free-Float
94.52%
Yield 2026 *
-
Yield 2027 * -
1 day-1.31%
3 months+38.63%
6 months+26.80%
Current year+25.57%
Current year 19.44
Extreme 19.44
27.42
1 year 16.06
Extreme 16.06
27.42
3 years 13.48
Extreme 13.48
36.2
5 years 13.48
Extreme 13.48
40.04
10 years 13.48
Extreme 13.48
40.04
Manager TitleAgeSince
Director of Finance/CFO 52 2022-04-30
Chief Executive Officer 50 2015-07-31
Chief Tech/Sci/R&D Officer 58 2025-11-05
Director TitleAgeSince
Director/Board Member 50 2015-02-28
Director/Board Member 73 2015-03-31
Director/Board Member 68 2015-03-31
Change 5-day change 1-year change 3-year change Capi.($)
-1.31%-.--% - - 3.28B
+4.16%+3.04%+49.37%+94.17% 74.41B
-3.11%-2.32%+23.28%+77.03% 59.26B
+0.89%-0.77%+5.80%+32.89% 47.14B
-0.96%-6.11%+26.70%+31.24% 42.91B
+0.36%+3.39%+350.59%+646.53% 44.13B
-0.20%-0.53%+6.84%+99.07% 40.79B
-0.54%+2.93%+9.50%+50.41% 30.77B
-2.68%+5.11%+33.11%+19.50% 29.31B
+2.33%-8.58%-24.55%+340.08% 23.71B
Average -0.11%-0.64%+53.40%+154.55% 43.6B
Weighted average by Cap. +0.23%-0.40%+58.36%+145.81%

Financials

2026 *2027 *
Net sales 50.57M 264M 44.95M 41.9M 38.19M 72.04M 4.87B 72.73M 508M 197M 2.48B 190M 186M 7.98B 130M 676M 115M 107M 97.81M 184M 12.47B 186M 1.3B 504M 6.36B 486M 476M 20.44B
Net income -454M -2.37B -403M -376M -343M -646M -43.69B -652M -4.56B -1.77B -22.28B -1.7B -1.67B -71.6B -449M -2.35B -399M -372M -339M -640M -43.28B -646M -4.51B -1.75B -22.07B -1.69B -1.65B -70.93B
Net Debt -708M -3.7B -630M -587M -535M -1.01B -68.22B -1.02B -7.11B -2.76B -34.79B -2.66B -2.6B -112B -749M -3.91B -665M -620M -565M -1.07B -72.1B -1.08B -7.52B -2.91B -36.77B -2.81B -2.75B -118B
Logo Denali Therapeutics Inc.
Denali Therapeutics Inc. is a biopharmaceutical company establishing a new class of biotherapeutics designed to cross the blood-brain barrier using its TransportVehicle platform. It is focused on building a portfolio of therapeutic candidates by investing in its TV franchises, i.e., Enzyme TV (ETV), Oligonucleotide TV (OTV), and Antibody TV (ATV), to advance programs for rare diseases, such as lysosomal storage diseases, and common diseases, such as Alzheimer's disease and Parkinson's disease. Its most advanced TV-enabled program is tividenofusp alfa (DNL310, ETV:IDS) for the potential treatment of mucopolysaccharidosis II (Hunter syndrome). TV-enabled clinical development portfolio also includes DNL126 (ETV:SGSH) for mucopolysaccharidosis IIIA (Sanfilippo syndrome type A), DNL593 (PTV:PGRN) for frontotemporal dementia-granulin, DNL628 (OTV:MAPT) for Alzheimer’s disease, and DNL952 (ETV:GAA) for Pompe disease. It is also pursuing opportunities in other disease areas including oncology.
Employees
503
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
-
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
20
Last Close Price
20.00USD
Average target price
36.06USD
Spread / Average Target
+80.31%

Quarterly revenue - Rate of surprise