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Valuation: Centessa Pharmaceuticals plc

Market Cap 6.15B 5.31B 4.89B 4.58B 8.6B 584B 8.73B 58B 22.57B 284B 23.06B 22.57B 984B P/E Ratio 2026 *
-25.5x
P/E Ratio 2027 * -22.7x
Enterprise Value 6.15B 5.31B 4.89B 4.58B 8.6B 584B 8.73B 58B 22.57B 284B 23.06B 22.57B 984B EV / Sales 2026 *
-
EV / Sales 2027 * 307x
Free-Float
78.43%
Yield 2026 *
-
Yield 2027 * -
1 day-0.13%
1 week+0.25%
Current month-0.10%
1 month+0.35%
3 months+50.85%
6 months+49.83%
Current year+58.82%
1 week 39.58
Extreme 39.58
39.83
1 month 39.56
Extreme 39.56
39.98
Current year 21.5
Extreme 21.5
40.26
1 year 12.05
Extreme 12.05
40.26
3 years 4.75
Extreme 4.75
40.26
5 years 2.88
Extreme 2.885
40.26
10 years 2.88
Extreme 2.885
40.26
Manager TitleAgeSince
Chief Executive Officer 40 2025-12-31
Director of Finance/CFO 53 2024-06-09
Chief Tech/Sci/R&D Officer - 2024-09-30
Director TitleAgeSince
Chairman 56 2020-10-31
Director/Board Member 45 2020-12-31
Director/Board Member 53 2020-12-31
Date Insider Type Main position Quantity % Market Cap.
04-30Tax

Chief Executive Officer

-604 0.0004%
03-25Fiscal year

Head of Human Resources

123,228 0.0922%
03-25Fiscal year

Executive/Senior Manager

71,994 0.0539%
Change 5-day change 1-year change 3-year change Capi.($)
-0.13%+0.25%+220.84%+748.72% 6.15B
-0.35%+0.97%-15.96%-12.73% 43.03B
+3.11%+3.11%+279.08%+501.52% 32.71B
+0.22%-1.08%+15.66%-15.65% 30.29B
+1.62%-2.08%-1.91%+24.64% 29.4B
+4.09%+0.93%+10.83%+18.78% 25.08B
-1.63%+2.88%+56.69%+113.41% 13.35B
+1.14%+3.62% - - 13.54B
-0.40%-1.29%+6.23%+7.63% 12.97B
-0.74%-1.62%+105.89%+74.92% 12.11B
Average +0.69%+1.33%+75.26%+162.36% 21.86B
Weighted average by Cap. +1.02%+1.45%+61.49%+115.57%

Financials

2026 *2027 *
Net sales - 20M 17.29M 15.93M 14.92M 27.98M 1.9B 28.4M 189M 73.44M 925M 75.06M 73.46M 3.2B
Net income -243M -210M -194M -181M -340M -23.13B -345M -2.3B -893M -11.25B -913M -893M -38.96B -262M -226M -209M -195M -366M -24.91B -372M -2.47B -962M -12.12B -983M -962M -41.95B
Net Debt - -
Logo Centessa Pharmaceuticals plc
Centessa Pharmaceuticals plc is a clinical-stage pharmaceutical company. The Company is developing a new class of potential therapies within its orexin receptor 2 (OX2R) agonist program for the treatment of excessive daytime sleepiness (EDS), impaired attention, cognitive deficits, fatigue and other symptoms across neurological, neurodegenerative and neuropsychiatric disorders. It also has an early-stage immuno-oncology program focused on its LockBody technology platform. Its OX2R agonist pipeline includes ORX750, its advanced OX2R agonist development candidate, and ORX142, ORX489 and OX2R agonists in preclinical development. Its ORX750, an investigational, orally administered, highly potent and selective OX2R agonist, is in a Phase IIa study of participants with narcolepsy type 1 (NT1), NT2 and idiopathic hypersomnia (IH). ORX142 is the second OX2R agonist development candidate being advanced for the treatment of neurological and neurodegenerative disorders and other symptoms.
Employees
129
Date Price Change Volume
26-06-12 39.72 $ -0.13% 1,322,753
26-06-11 39.77 $ +0.20% 871,057
26-06-10 39.69 $ -0.18% 1,780,789
26-06-09 39.76 $ +0.15% 2,302,698
26-06-08 39.70 $ +0.20% 553,287
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
-
Sell
Consensus
Buy
Mean consensus
OUTPERFORM
Number of Analysts
12
Last Close Price
39.72USD
Average target price
44.17USD
Spread / Average Target
+11.20%

Quarterly revenue - Rate of surprise

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