Adaptimmune Therapeutics PLC is focused on pre-clinical programs, including PRAME and CD70-directed T-cell therapies, and its allogeneic pipeline. PRAME is highly expressed across a range of solid tumors, including ovarian, endometrial, lung and breast cancers. The CD70 program targets the CD70 antigen, which is expressed across a range of hematological malignancies (acute myeloid leukemia and lymphoma) and solid tumors (renal cell carcinoma). It is using TRuC technology to develop a T-cell therapy (ADP-520) against CD70, with membrane bound IL-15 to enhance persistence. ADP-520 is in pre-clinical testing. TRuC technology combines the targeting of CAR-T cells with T-cell TCR signaling.

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272

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Pharmaceuticals

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Date	Price	Change	Volume
26-08-07	US$0.0300	-3.23%	125,818
26-08-06	US$0.0310	+12.73%	152,909
26-08-05	US$0.0275	-14.06%	35,909
26-08-04	US$0.0320	+10.34%	345,408
26-08-03	US$0.0290	-8.81%	86,045

Delayed Quote OTC Markets

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Market Closed - OTC Markets Other stock markets 15:59:09 2026-08-07 EDT			5-day change	1st Jan Change
0.0300 ^USD	-3.23%		-5.66%	+15.38%

05-18	Adaptimmune Therapeutics plc Reports Earnings Results for the Full Year Ended December 31, 2025	CI
11-17	Adaptimmune Therapeutics plc Announces CEO Changes	CI

Market Cap	7.95M 6.88M 6.42M 5.89M 11.08M 757M 11.26M 75.36M 29.58M 379M 29.86M 29.21M 1.25B	P/E 2024	-1.8x	P/E 2025	0.33x
Enterprise Value	-3.92M -3.39M -3.16M -2.9M -5.46M -373M -5.55M -37.13M -14.57M -187M -14.71M -14.39M -618M	EV / Sales 2024	0.34x	EV / Sales 2025	-0.84x
Free-Float	14.03%	Yield 2024 *	-	Yield 2025	-

05-18	Adaptimmune Therapeutics plc Reports Earnings Results for the Full Year Ended December 31, 2025	CI
11-17	Adaptimmune Therapeutics plc Announces CEO Changes	CI
11-17	Adaptimmune Therapeutics plc Announces Leadership Changes	CI
25-10-27	Evaxion Names Helen Tayton-Martin as Chief Executive Officer	MT
25-10-26	Adaptimmune Therapeutics plc(OTCPK:ADAP.Y) dropped from NASDAQ Composite Index	CI
25-10-24	European Equities Traded in the US as American Depositary Receipts Flat in Friday Trading	MT
25-10-23	European Equities Traded in the US as American Depositary Receipts Rise in Thursday Trading	MT
25-10-22	European Equities Traded in the US as American Depositary Receipts Rise in Wednesday Trading	MT
25-10-21	European Equities Traded in the US as American Depositary Receipts Decline in Tuesday Trading	MT
25-10-20	Top Midday Decliners	MT
25-10-20	European Equities Close Mostly Higher in Monday Trading; UK Sentiment Sees 'Some of the Gloom Lift'	MT
25-10-20	European Equities Traded in the US as American Depositary Receipts Rise in Monday Trading	MT
25-10-20	Adaptimmune Therapeutics to Voluntarily Delist From Nasdaq	MT

25-07-30	Guggenheim Downgrades Adaptimmune Therapeutics to Neutral From Buy	MT
25-07-29	HC Wainwright Downgrades Adaptimmune Therapeutics to Neutral From Buy	MT
25-06-26	Mizuho Downgrades Adaptimmune Therapeutics to Neutral From Outperform, Cuts Price Target to $0.50 From $1.50 on Solvency Concerns	MT
24-11-27	Mizuho Cuts Price Target on Adaptimmune Therapeutics to $1.50 From $3, Keeps Outperform Rating	MT
24-07-30	HC Wainwright Starts Adaptimmune Therapeutics With Buy Rating, $4 Price Target	MT

Adaptimmune Therapeutics plc Stock

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ADAPY

US00653A1079

Pharmaceuticals

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11-17	Adaptimmune Announces Changes to Board and Executive Leadership Team	NE
25-10-20	Adaptimmune Announces Delisting from Nasdaq	NE
25-08-13	Adaptimmune Reports Q2 Financial Results and Provides Business Update	NE
25-07-28	Adaptimmune Announces Entry into Definitive Agreement for Sale of TECELRA, lete-cel, afami-cel and uza-cel Cell Therapies to US WorldMeds	NE
25-05-13	Adaptimmune Reports Q1 Financial Results and Provides Business Update	NE

24-05-30	Galapagos gaat samenwerken met Adaptimmune
24-04-12	Roche: Genentech met fin à la collaboration avec Adaptimmune Therapeutics
24-04-12	Roche-Tochter Genentech beendet Zusammenarbeit mit Adaptimmune Therapeutics
23-04-11	GSK : Adaptimmune reprend les droits de deux programmes
21-09-07	Aktien Schweiz Schluss: SMI unter Druck

1 day	-3.23%
1 week	-5.66%
Current month	-5.66%
1 month	-16.67%
3 months	+1,900.00%
Current year	+15.38%

1 week	0.02	0.03
1 month	0.02	0.04
Current year	0	0.05
1 year	0	0.28
3 years	0	2.05
5 years	0	6.86
10 years	0	14.62

Manager	Title	Age	Since
Christopher Hill CEO	Chief Executive Officer	46	2025-11-13
Juli P. Miller IRC	Investor Relations Contact	-	2016-07-31
Phil Bassett PRN	Corporate Officer/Principal	-	-

Director	Title	Age	Since
Lawrence Alleva CHM	Chairman	76	2025-11-13
Garry Menzel BRD	Director/Board Member	61	2023-05-31
Christopher Hill BRD	Director/Board Member	46	2025-11-13

Date	Insider	Type	Main position	Quantity	% Market Cap.
9/2/25	Gavin Wood	Sell	Chief Financial Officer	96,000	0.0060%
8/28/25	William Bertrand	Sell	Compliance Officer	207,000	0.0130%
8/15/25	NEA Management Co. LLC	Sell	Company	19,500,000	7.3571%

Add to a list 0 selected To use this feature you must be a member Log in Sign up	Change	5-day change	1-year change	3-year change	Capi.($)
ADAPTIMMUNE THERAPEUTICS PLC	-3.23%	-5.66%	-61.29%	-96.51%	7.95M
REGENERON PHARMACEUTICALS, INC.	+1.59%	+2.85%	+39.32%	+0.52%	78.32B
SAMSUNG BIOLOGICS CO.,LTD.	+2.77%	+4.78%	-0.98%	+28.10%	51.1B
UCB	-0.84%	+0.09%	+20.92%	+175.02%	49.18B
CSL LIMITED	-0.13%	+7.42%	-49.33%	-50.09%	44.71B
BIOGEN INC.	+0.80%	+2.46%	+59.13%	-24.15%	30.72B
INCYTE CORPORATION	+1.84%	+0.87%	+53.80%	+86.83%	24.44B
MODERNA, INC.	+9.86%	+7.94%	+126.53%	-40.68%	23.62B
INNOVENT BIOLOGICS, INC.	+4.29%	+9.40%	+3.95%	+230.49%	21.05B
SWEDISH ORPHAN BIOVITRUM AB	+1.66%	-3.70%	+66.13%	+121.72%	16.61B
Average	+1.86%	+3.10%	+25.82%	+43.13%	33.98B
Weighted average by Cap.	+1.88%	+4.29%	+26.94%	+44.55%

	2024	2025
Net sales	178M 154M 144M 132M 248M 16.94B 252M 1.69B 662M 8.49B 669M 654M 28.08B	5.92M 5.12M 4.79M 4.39M 8.26M 564M 8.39M 56.14M 22.04M 283M 22.25M 21.76M 934M
Net income	-70.81M -61.25M -57.2M -52.47M -98.7M -6.74B -100M -671M -263M -3.38B -266M -260M -11.17B	25.21M 21.8M 20.36M 18.68M 35.13M 2.4B 35.69M 239M 93.76M 1.2B 94.65M 92.58M 3.98B
Net Debt	-77.4M -66.95M -62.52M -57.35M -108M -7.37B -110M -734M -288M -3.69B -291M -284M -12.21B	-11.87M -10.27M -9.59M -8.8M -16.54M -1.13B -16.81M -112M -44.15M -566M -44.57M -43.59M -1.87B