![Barbara Klencke](data:image/svg+xml,<svg xmlns="http://www.w3.org/2000/svg" width="16" height="16" fill="%231b1b1b" class="bi bi-person-fill" viewBox="0 0 16 16"><path d="M3 14s-1 0-1-1 1-4 6-4 6 3 6 4-1 1-1 1zm5-6a3 3 0 1 0 0-6 3 3 0 0 0 0 6"/></svg>)
Barbara Klencke
Chief Tech/Sci/R&D Officer at
ALX ONCOLOGY HOLDINGS INC.
Net worth: 374 714 $ as of 2026-05-30
Profile
Barbara J.
Klencke is currently an Independent Director at Xencor, Inc. since 2023, Immune-Onc Therapeutics, Inc. since 2022, and TScan Therapeutics, Inc. since 2023.
Dr. Klencke is also set to be Chief Medical Officer at ALX Oncology Holdings, Inc. starting in 2025.
Former roles include Medical Director at Chiron Corp.
from 2002 to 2003, Group Medical Director-Product Development at Genentech, Inc. from 2003 to 2011, Senior Vice President-Global Development at Onyx Pharmaceuticals, Inc. from 2011 to 2015, Chief Medical & Development Officer at Sierra Oncology, Inc. from 2015 to 2022, Independent Director at Lexent Bio, Inc. from 2017 to 2020, Independent Director at eFFECTOR Therapeutics, Inc. from 2021 to 2024, and Assistant Professor-Medicine in Oncology at the University of California from 1995 to 2002.
Education includes undergraduate studies at Indiana University and a doctorate from the University of California, Davis.
Known holdings in public companies
| Company | Date | Number of shares | Valuation | Valuation date |
|---|---|---|---|---|
| 2026-04-15 | 120,000 ( 0.09% ) | 228 000 $ | 2026-05-30 | |
| 2026-05-19 | 70,000 ( 0.11% ) | 75 600 $ | 2026-05-30 | |
XENCOR, INC. 0.01% | 2026-02-27 | 5,986 ( 0.01% ) | 71 114 $ | 2026-05-30 |
Barbara Klencke active positions
| Companies | Position | Start |
|---|---|---|
| TSCAN THERAPEUTICS, INC. | Director/Board Member | 2023-04-05 |
| XENCOR, INC. | Director/Board Member | 2023-09-14 |
| ALX ONCOLOGY HOLDINGS INC. | Chief Tech/Sci/R&D Officer | 2025-09-16 |
Immune-Onc Therapeutics, Inc.
 Immune-Onc Therapeutics, Inc. BiotechnologyHealth Technology Operates as a clinical-stage biopharmaceutical company advancing novel therapies that target myeloid cells | Director/Board Member | 2022-11-07 |
Former positions of Barbara Klencke
| Companies | Position | End |
|---|---|---|
| EFFECTOR THERAPEUTICS, INC. | Director/Board Member | 2024-06-20 |
| SIERRA ONCOLOGY, INC. | Chief Tech/Sci/R&D Officer | 2022-06-30 |
Lexent Bio, Inc.
 Lexent Bio, Inc. Financial ConglomeratesFinance Develops novel liquid biopsy technologies to manage cancer | Director/Board Member | 2019-12-31 |
Onyx Pharmaceuticals, Inc.
 Onyx Pharmaceuticals, Inc. Pharmaceuticals: MajorHealth Technology Operates as a biopharmaceutical company that provide therapeutics for cancer | Corporate Officer/Principal | 2015-05-31 |
Genentech, Inc.
 Genentech, Inc. BiotechnologyHealth Technology Operates as a biotechnology company that develops medicines for cancer peoples | Corporate Officer/Principal | 2010-12-31 |
Training of Barbara Klencke
Experiences
Positions held
Active
Inactive
Listed companies
Private companies
Connections
83
1st degree connections
13
1st degree companies
Male
Female
Members of the board
Executives
Linked companies
| Private companies | 13 |
|---|---|
Chiron Corp.
 Chiron Corp. Medical SpecialtiesHealth Technology Provides nucleic acid test for blood screening | Health Technology |
Genentech, Inc.
Genentech, Inc. BiotechnologyHealth Technology Operates as a biotechnology company that develops medicines for cancer peoples | Health Technology |
Onyx Pharmaceuticals, Inc.
Onyx Pharmaceuticals, Inc. Pharmaceuticals: MajorHealth Technology Operates as a biopharmaceutical company that provide therapeutics for cancer | Health Technology |
Sierra Oncology, Inc.
 Sierra Oncology, Inc. BiotechnologyHealth Technology Develops novel therapeutic approaches for cancer and other diseases | Health Technology |
Xencor, Inc.
 Xencor, Inc. BiotechnologyHealth Technology Develops therapeutics to treat autoimmune and allergic diseases, cancer and other conditions | Health Technology |
Indiana University
 Indiana University Other Consumer ServicesConsumer Services Functions as a College/University | Consumer Services |
University of California, Davis
 University of California, Davis Other Consumer ServicesConsumer Services Functions as a College/University | Consumer Services |
University of California
 University of California Other Consumer ServicesConsumer Services Functions as a College/University | Consumer Services |
Immune-Onc Therapeutics, Inc.
Immune-Onc Therapeutics, Inc. BiotechnologyHealth Technology Operates as a clinical-stage biopharmaceutical company advancing novel therapies that target myeloid cells | Health Technology |
Lexent Bio, Inc.
Lexent Bio, Inc. Financial ConglomeratesFinance Develops novel liquid biopsy technologies to manage cancer | Finance |
TScan Therapeutics, Inc.
 TScan Therapeutics, Inc. BiotechnologyHealth Technology Develops T-cell therapies for cancer patients | Health Technology |
ALX Oncology Holdings, Inc.
 ALX Oncology Holdings, Inc. BiotechnologyHealth Technology Operates as clinical stage immuno-oncology company, which develops therapies for cancer | Health Technology |
eFFECTOR Therapeutics, Inc.
 eFFECTOR Therapeutics, Inc. BiotechnologyHealth Technology Operates as a oncology company which develops therapies for cancer | Health Technology |
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