Business description: Scilex Holding Company

Scilex Holding Company is focused on acquiring, developing and commercializing non-opioid pain management products for the treatment of acute and chronic pain. The Company’s commercial products include ZTlidoO (lidocaine topical system) 1.8% for the relief of neuropathic pain associated with postherpetic neuralgia (PHN); ELYXYB, a ready-to-use oral solution for the acute treatment of migraine, with or without aura, in adults; and GLOPERBA, the liquid oral version of the anti-gout medicine colchicine indicated for the prophylaxis of painful gout flares in adults. In addition, it focuses on product candidates, including SP-102 (10 mg, dexamethasone sodium phosphate viscous gel) (SEMDEXAO), an epidural injections formulation to treat lumbosacral radicular pain, or sciatica; SP-103 (lidocaine topical system) 5.4%, a ZTlido formulation, for the treatment of acute pain; and SP-104 (4.5 mg, low-dose naltrexone hydrochloride delayed-release capsules) (SP-104) for fibromyalgia treatment.

Number of employees: 34

Sales by Activity: Scilex Holding Company

Fiscal Period: December 2021 (USD) 2022 (USD) 2023 (USD) 2024 (USD) 2025 (USD)

Development of Non-Opioid Products

31.32M 38.03M 46.74M 56.59M 30.25M

Geographical breakdown of sales: Scilex Holding Company

Fiscal Period: December 2021 (USD) 2022 (USD) 2023 (USD) 2024 (USD) 2025 (USD)

United States

31.32M 38.03M 46.74M 56.59M 30.25M

Executive Committee: Scilex Holding Company

Manager TitleAgeSince
Chief Executive Officer 61 2025-08-16
Director of Finance/CFO 53 2023-09-21
Chief Tech/Sci/R&D Officer - 2021-12-31
Compliance Officer - -
Chief Tech/Sci/R&D Officer 57 -

Composition of the Board of Directors: Scilex Holding Company

Director TitleAgeSince
Director/Board Member 62 2022-11-09
Director/Board Member 53 2025-09-21
Director/Board Member 62 2023-09-21
Director/Board Member 62 2023-09-21
Chairman 61 2023-09-21

Shareholders: Scilex Holding Company

NameEquities%Valuation
SCLX Stock Acquisition JV LLC
17.17 %
1,458,263 17.17 % 10 M $
Armistice Capital LLC
5.614 %
476,674 5.614 % 3 M $
Vanguard Capital Management LLC (Pennsylvania)
3.11 %
264,050 3.11 % 2 M $
BlackRock Institutional Trust Co. NA
1.146 %
97,289 1.146 % 647 945 $
Vanguard Fiduciary Trust Co.
0.5016 %
42,595 0.5016 % 283 683 $
NameEquities%Valuation
SCLX Stock Acquisition JV LLC
100 %
29,057,097 100 % 194 M $
NameEquities%Valuation
Cruiser Capital Advisors LLC
0.3795 %
49,999 0.3795 % 5 500 $
Virtu Financial LLC
0.3615 %
47,634 0.3615 % 5 240 $
Landscape Capital Management LLC
0.3326 %
43,824 0.3326 % 4 821 $
Clear Street Group, Inc.
0.0219 %
2,880 0.0219 % 317 $

Holdings: Scilex Holding Company

NameEquities%Valuation
Semnur Pharmaceuticals, Inc.
81.91%
188,554,849 81.91% 1 414 M $
213,766,229 30.6% 155 M $

Company details: Scilex Holding Company

Scilex Holding Co.

960 San Antonio Road

94303, Palo Alto

+

http://www.scilexholding.com
address Scilex Holding Company(SCLX)

Specialty & Advanced Pharmaceuticals

Change 5d. change 1-year change 3-years change Capi.($)
-11.76%-38.12%+72.07%-96.31% 55M
+0.04%+3.20%-8.47%-31.68% 57.75B
-0.99%-1.32%+10.37%-10.46% 7.77B
+3.57%+2.85%+0.82%+101.30% 7.6B
-0.80%-1.30%+9.07%+39.86% 5.33B
-2.31%-7.64%-21.08%+54.49% 4.4B
+3.67%+2.68%+5.23%-20.36% 3.18B
-4.19%+1.52%+55.74%+37.52% 2.99B
-0.51%+0.65%+21.35%+18.36% 2.55B
+0.32%+0.26%+82.56%+35.23% 2.04B
Average -1.29%-2.50%+22.77%+12.80% 9.37B
Weighted average by Cap. +0.06%+1.77%-0.39%-5.64%
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