Cash flow Protagonist Therapeutics, Inc.

Equities

PTGX

US74366E1029

Biotechnology & Medical Research

Market Closed - Nasdaq Other stock markets 16:00:00 2026-01-22 EST			5-day change	1st Jan Change
84.79 ^USD	+1.07%		+0.05%	-2.92%

01-13	Protagonist Therapeutics, Inc. Presents at 44th Annual J.P. Morgan Healthcare Conference, Jan-13-2026 08:15 AM
01-05	Takeda and Protagonist Announce Submission of New Drug Application for Rusfertide for Treatment of Polycythemia Vera	CI

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Published financial data: PROTAGONIST THERAPEUTICS, INC.

Annual

Quarterly

Halfyear

YTD

LTM

Fiscal Period: December	2020	2021	2022	2023	2024
Revenues	28.63M	27.36M	26.58M	60M	434M
Total Revenues	28.63M	27.36M	26.58M	60M	434M
Gross Profit	28.63M	27.36M	26.58M	60M	434M
Selling General & Admin Expenses, Total	18.64M	27.2M	31.74M	33.49M	43.46M
R&D Expenses	74.51M	126M	126M	120M	138M
Other Operating Expenses, Total	93.14M	153M	158M	154M	182M
Operating Income	-64.52M	-126M	-131M	-93.65M	253M
Interest Expense, Total	-598K	-	-	-	-
Interest And Investment Income	900K	443K	4.06M	14.9M	26.32M
Net Interest Expenses	302K	443K	4.06M	14.9M	26.32M
Currency Exchange Gains (Loss)	-46K	-149K	-80K	-201K	250K
Other Non Operating Income (Expenses)	-	-	-	-	-
EBT, Excl. Unusual Items	-64.26M	-126M	-127M	-78.96M	279M
Other Unusual Items	-585K	-	-	-	-
EBT, Incl. Unusual Items	-64.84M	-126M	-127M	-78.96M	279M
Income Tax Expense	1.3M	-	-	-	4.22M
Earnings From Continuing Operations	-66.15M	-126M	-127M	-78.96M	275M
Net Income to Company	-66.15M	-126M	-127M	-78.96M	275M
Net Income - (IS)	-66.15M	-126M	-127M	-78.96M	275M
Preferred Dividend and Other Adjustments	-	-	-	-	-
Net Income to Common Incl Extra Items	-66.15M	-126M	-127M	-78.96M	275M
Net Income to Common Excl. Extra Items	-66.15M	-126M	-127M	-78.96M	275M
Per Share Items
Net EPS - Basic	-1.92	-2.71	-2.6	-1.39	4.47
Basic EPS - Continuing Operations	-1.92	-2.71	-2.6	-1.39	4.47
Basic Weighted Average Shares Outstanding	34.4M	46.32M	49.04M	56.76M	61.57M
Net EPS - Diluted	-1.92	-2.71	-2.6	-1.39	4.23
Diluted EPS - Continuing Operations	-1.92	-2.71	-2.6	-1.39	4.23
Diluted Weighted Average Shares Outstanding	34.4M	46.32M	49.04M	56.76M	65.08M
Normalized Basic EPS	-1.17	-1.69	-1.62	-0.87	2.84
Normalized Diluted EPS	-1.17	-1.69	-1.62	-0.87	2.68
Supplemental Items
EBITDA	-63.73M	-125M	-130M	-92.68M	254M
EBITA	-64.52M	-126M	-131M	-93.65M	253M
EBIT	-64.52M	-126M	-131M	-93.65M	253M
EBITDAR	-62.04M	-123M	-128M	-90.48M	256M
Effective Tax Rate - (Ratio)	-2.01	-	-	-	1.51
Current Domestic Taxes	-	-	-	-	4.22M
Current Foreign Taxes	-88K	-	-	-	-
Total Current Taxes	-88K	-	-	-	4.22M
Deferred Foreign Taxes	1.39M	-	-	-	-
Total Deferred Taxes	1.39M	-	-	-	-
Normalized Net Income	-40.16M	-78.47M	-79.62M	-49.35M	175M
Interest on Long-Term Debt	698K	-	-	-	-
Supplemental Operating Expense Items
General and Administrative Expenses	18.64M	27.2M	31.74M	33.49M	43.46M
Research And Development Expense From Footnotes	75.98M	129M	126M	120M	138M
Net Rental Expense, Total	1.69M	1.87M	2.21M	2.2M	2.48M
Imputed Operating Lease Interest Expense	702K	-	-	-	-
Imputed Operating Lease Depreciation	983K	-	-	-	-
Stock-Based Comp., R&D Exp. (Total)	4.12M	9M	14.72M	17.06M	20.92M
Stock-Based Comp., G&A Exp. (Total)	3.78M	7.4M	9.48M	12.23M	16.64M
Total Stock-Based Compensation	7.9M	16.4M	24.2M	29.29M	37.55M

Fiscal Period: December	2020	2021	2022	2023	2024
Assets
Cash And Equivalents	117M	124M	126M	187M	97.25M
Short Term Investments	188M	203M	112M	155M	322M
Total Cash And Short Term Investments	306M	327M	237M	342M	419M
Accounts Receivable, Total	2.43M	1.57M	10K	10M	165M
Other Receivables	1.4M	3.77M	42K	332K	3.49M
Total Receivables	3.82M	5.33M	52K	10.33M	168M
Prepaid Expenses	5.97M	8.5M	5.67M	3.63M	4.24M
Restricted Cash	10K	-	-	-	-
Other Current Assets, Total	-	-	-	-	-
Total Current Assets	316M	341M	243M	356M	592M
Gross Property Plant And Equipment	9.88M	10.99M	9.88M	8.38M	19.64M
Accumulated Depreciation	-3.47M	-4.26M	-5.25M	-6.23M	-7.04M
Net Property Plant And Equipment	6.41M	6.73M	4.63M	2.15M	12.61M
Long-term Investments	2M	-	-	-	140M
Deferred Tax Assets Long-Term	-	-	-	-	-
Other Long-Term Assets, Total	450K	225K	225K	225K	225K
Total Assets	324M	348M	248M	358M	745M
Liabilities
Accounts Payable, Total	3.08M	1.6M	3.64M	772K	1.62M
Accrued Expenses, Total	18.42M	37.31M	24.54M	19.26M	23.62M
Current Portion of Leases	1.46M	2.2M	2.52M	1.14M	510K
Current Income Taxes Payable	-	-	-	-	2.69M
Unearned Revenue Current, Total	14.48M	1.6M	-	-	18.89M
Other Current Liabilities	2.81M	1.31M	484K	102K	74K
Total Current Liabilities	40.24M	44.02M	31.18M	21.27M	47.4M
Long-Term Debt	-	-	-	-	-
Long-Term Leases	4.5M	3.66M	1.14M	-	10.36M
Unearned Revenue Non Current	-	-	-	-	11.68M
Other Non Current Liabilities	121K	-	-	-	-
Total Liabilities	44.86M	47.67M	32.32M	21.27M	69.43M
Preferred Stock Convertible	-	-	-	-	-
Preferred Stock - Others	-	-	-	-	-
Total Preferred Equity	-	-	-	-	-
Common Stock, Total	-	-	-	1K	1K
Additional Paid In Capital	563M	710M	753M	952M	1.02B
Retained Earnings	-284M	-409M	-537M	-616M	-341M
Comprehensive Income and Other	28K	-299K	-359K	-105K	-82K
Total Common Equity	280M	300M	216M	337M	675M
Total Equity	280M	300M	216M	337M	675M
Total Liabilities And Equity	324M	348M	248M	358M	745M
Supplemental Items
ECS Total Shares Outstanding on Filing Date	43.81M	48.41M	51.28M	58.27M	61.38M
ECS Total Common Shares Outstanding	43.75M	47.84M	49.34M	57.71M	61.04M
Book Value / Share	6.39	6.27	4.37	5.83	11.06
Tangible Book Value	280M	300M	216M	337M	675M
Tangible Book Value Per Share	6.39	6.27	4.37	5.83	11.06
Total Debt	5.96M	5.86M	3.66M	1.14M	10.87M
Net Debt	-302M	-321M	-234M	-340M	-548M
Debt Equivalent Oper. Leases	13.48M	14.97M	17.7M	17.58M	19.81M
Account Code - Inventory Valuation	3	-	3	3	3
Machinery, Total	4.19M	5.18M	5.91M	6.47M	7.8M
Full Time Employees	79	118	105	112	126

Fiscal Period: December	2020	2021	2022	2023	2024
Net Income	-66.15M	-126M	-127M	-78.96M	275M
Depreciation & Amortization - CF	2.56M	2.78M	3.37M	3.31M	2.9M
Depreciation & Amortization, Total	2.56M	2.78M	3.37M	3.31M	2.9M
Amortization of Deferred Charges, Total - (CF)	159K	-	-	-	-
(Gain) Loss From Sale Of Asset	-	-	-	-	-
(Gain) Loss on Sale of Investments - (CF)	37K	1.83M	-549K	-4.57M	-8.88M
Stock-Based Compensation (CF)	7.9M	16.4M	24.2M	29.29M	37.55M
Other Operating Activities, Total	2.14M	-121K	-	194K	-
Change In Accounts Receivable	4.33M	860K	1.56M	-9.99M	-155M
Change In Accounts Payable	309K	-1.39M	2.04M	-2.87M	842K
Change in Unearned Revenues	-27.05M	-12.88M	-1.6M	-	30.57M
Change In Income Taxes	-	-	-	-	2.69M
Change in Other Net Operating Assets	3.28M	10.21M	-9.77M	-6.65M	-1.71M
Cash from Operations	-72.48M	-108M	-108M	-70.24M	184M
Capital Expenditure	-471K	-1.1M	-795K	-609K	-1.36M
Sale of Property, Plant, and Equipment	-	-	-	-	-
Investment in Marketable and Equity Securities, Total	-90.49M	-14.76M	92.26M	-38.65M	-298M
Cash from Investing	-90.96M	-15.86M	91.47M	-39.26M	-299M
Long-Term Debt Issued, Total	-	-	-	-	-
Total Debt Issued	-	-	-	-	-
Long-Term Debt Repaid, Total	-10.52M	-	-	-	-
Total Debt Repaid	-10.52M	-	-	-	-
Issuance of Common Stock	258M	130M	19M	171M	26.45M
Repurchase of Common Stock	-	-189K	-188K	-769K	-600K
Issuance of Preferred Stock	-	-	-	-	-
Other Financing Activities, Total	-14K	-	25K	-	-
Cash from Financing	248M	130M	18.84M	170M	25.85M
Foreign Exchange Rate Adjustments	175K	-126K	-90K	-	-
Net Change in Cash	84.35M	6.07M	2.08M	60.98M	-89.48M
Supplemental Items
Cash Interest Paid	438K	-	-	-	-
Cash Income Tax Paid (Refund)	-	-	-	-	1.53M
Levered Free Cash Flow	-23.42M	-61.59M	-60.37M	-43.31M	65.11M
Unlevered Free Cash Flow	-23.2M	-61.59M	-60.37M	-43.31M	65.11M
Change In Net Working Capital	-7.13M	1M	5.04M	16.77M	132M
Net Debt Issued / Repaid	-10.52M	-	-	-	-

Fiscal Period: December	2020	2021	2022	2023	2024
Profitability
Return on Assets	-16.82	-23.4	-27.57	-19.32	28.66
Return on Total Capital	-21.08	-26.6	-31.27	-21.01	30.87
Return On Equity %	-36.79	-43.32	-49.41	-28.59	54.39
Return on Common Equity	-36.79	-43.32	-49.41	-28.59	54.39
Margin Analysis
Gross Profit Margin %	100	100	100	100	100
SG&A Margin	65.1	99.41	119.4	55.82	10
EBITDA Margin %	-222.6	-457.04	-490.35	-154.46	58.39
EBITA Margin %	-225.36	-460.01	-494.24	-156.09	58.2
EBIT Margin %	-225.36	-460.01	-494.24	-156.09	58.2
Income From Continuing Operations Margin %	-231.07	-458.94	-479.26	-131.59	63.34
Net Income Margin %	-231.07	-458.94	-479.26	-131.59	63.34
Net Avail. For Common Margin %	-231.07	-458.94	-479.26	-131.59	63.34
Normalized Net Income Margin	-140.29	-286.83	-299.54	-82.24	40.2
Levered Free Cash Flow Margin	-81.79	-225.13	-227.12	-72.18	14.99
Unlevered Free Cash Flow Margin	-81.04	-225.13	-227.12	-72.18	14.99
Asset Turnover
Asset Turnover	0.12	0.08	0.09	0.2	0.79
Fixed Assets Turnover	4.05	4.16	4.68	17.71	58.88
Receivables Turnover (Average Receivables)	6.24	13.71	33.73	11.99	4.96
Short Term Liquidity
Current Ratio	7.84	7.74	7.8	16.71	12.48
Quick Ratio	7.69	7.55	7.61	16.54	12.39
Operating Cash Flow to Current Liabilities	-1.8	-2.45	-3.47	-3.3	3.89
Days Sales Outstanding (Average Receivables)	58.69	26.63	10.82	30.45	73.72
Long Term Solvency
Total Debt/Equity	2.13	1.95	1.7	0.34	1.61
Total Debt / Total Capital	2.09	1.92	1.67	0.34	1.58
LT Debt/Equity	1.61	1.22	0.53	-	1.53
Long-Term Debt / Total Capital	1.58	1.2	0.52	-	1.51
Total Liabilities / Total Assets	13.83	13.71	13.04	5.94	9.32
EBIT / Interest Expense	-107.89	-	-	-	-
EBITDA / Interest Expense	-103.75	-	-	-	-
(EBITDA - Capex) / Interest Expense	-104.54	-	-	-	-
Total Debt / EBITDA	-0.1	-0.05	-0.03	-0.01	0.04
Net Debt / EBITDA	4.87	2.61	1.82	3.76	-2.14
Total Debt / (EBITDA - Capex)	-0.1	-0.05	-0.03	-0.01	0.04
Net Debt / (EBITDA - Capex)	4.83	2.58	1.81	3.74	-2.15
Growth Over Prior Year
Total Revenues, 1 Yr. Growth %	12.29K	-4.44	-2.84	125.73	624.06
Gross Profit, 1 Yr. Growth %	12.29K	-4.44	-2.84	125.73	624.06
EBITDA, 1 Yr. Growth %	-20.16	96.69	4.24	-28.9	-373.72
EBITA, 1 Yr. Growth %	-19.88	95.06	4.39	-28.71	-369.98
EBIT, 1 Yr. Growth %	-19.88	95.06	4.39	-28.71	-369.98
Earnings From Cont. Operations, 1 Yr. Growth %	-14.3	89.8	1.47	-38.02	-448.54
Net Income, 1 Yr. Growth %	-14.3	89.8	1.47	-38.02	-448.54
Normalized Net Income, 1 Yr. Growth %	-17.49	95.38	1.47	-38.02	-453.88
Diluted EPS Before Extra, 1 Yr. Growth %	-35.48	40.93	-4.07	-46.45	-404.11
Accounts Receivable, 1 Yr. Growth %	-64.09	-35.45	-99.36	99.9K	1.55K
Net Property, Plant and Equip., 1 Yr. Growth %	-16.98	5.02	-31.3	-53.55	486.64
Total Assets, 1 Yr. Growth %	109.45	7.16	-28.69	44.38	108.05
Tangible Book Value, 1 Yr. Growth %	249.66	7.3	-28.14	56.15	100.58
Common Equity, 1 Yr. Growth %	249.66	7.3	-28.14	56.15	100.58
Cash From Operations, 1 Yr. Growth %	74.55	48.81	0.25	-35.05	-362.19
Capital Expenditures, 1 Yr. Growth %	-51.29	133.76	-27.79	-23.4	122.5
Levered Free Cash Flow, 1 Yr. Growth %	-35.27	163.02	-1.98	-28.27	-250.35
Unlevered Free Cash Flow, 1 Yr. Growth %	-35.72	167.28	-1.98	-28.27	-250.35
Compound Annual Growth Rate Over Two Years
Total Revenues, 2 Yr. CAGR %	-3.79	988.25	-3.64	48.1	304.27
Gross Profit, 2 Yr. CAGR %	-3.79	988.25	-3.64	48.1	304.27
EBITDA, 2 Yr. CAGR %	23.56	25.18	43.19	-13.91	39.51
EBITA, 2 Yr. CAGR %	23.54	25.02	42.7	-13.73	38.73
EBIT, 2 Yr. CAGR %	23.54	25.02	42.7	-13.73	38.73
Earnings From Cont. Operations, 2 Yr. CAGR %	30.36	27.54	38.77	-20.7	46.97
Net Income, 2 Yr. CAGR %	30.36	27.54	38.77	-20.7	46.97
Normalized Net Income, 2 Yr. CAGR %	27.19	26.97	40.8	-20.7	48.1
Diluted EPS Before Extra, 2 Yr. CAGR %	5.12	-4.65	16.27	-28.36	27.55
Accounts Receivable, 2 Yr. CAGR %	-27.28	-51.85	-93.58	152.7	12.75K
Net Property, Plant and Equip., 2 Yr. CAGR %	172.89	-6.62	-15.06	-43.51	65.08
Total Assets, 2 Yr. CAGR %	52.53	49.81	-12.59	1.46	73.31
Tangible Book Value, 2 Yr. CAGR %	57.64	93.7	-12.19	5.93	76.98
Common Equity, 2 Yr. CAGR %	57.64	93.7	-12.19	5.93	76.98
Cash From Operations, 2 Yr. CAGR %	20.47	61.17	22.14	-19.31	30.5
Capital Expenditures, 2 Yr. CAGR %	-1.56	6.7	29.92	-25.63	30.55
Levered Free Cash Flow, 2 Yr. CAGR %	-21.04	30.48	60.57	-16.15	3.85
Unlevered Free Cash Flow, 2 Yr. CAGR %	-21.4	30.68	61.86	-16.15	3.85
Compound Annual Growth Rate Over Three Years
Total Revenues, 3 Yr. CAGR %	12.58	-4	386.39	27.97	151.35
Gross Profit, 3 Yr. CAGR %	12.58	-4	386.39	27.97	151.35
EBITDA, 3 Yr. CAGR %	19.34	44.15	17.77	13.39	26.59
EBITA, 3 Yr. CAGR %	19.4	43.86	17.72	13.23	26.18
EBIT, 3 Yr. CAGR %	19.4	43.86	17.72	13.23	26.18
Earnings From Cont. Operations, 3 Yr. CAGR %	21.42	47.75	18.18	6.08	29.9
Net Income, 3 Yr. CAGR %	21.42	47.75	18.18	6.08	29.9
Normalized Net Income, 3 Yr. CAGR %	20.25	46.75	17.83	7.11	30.56
Diluted EPS Before Extra, 3 Yr. CAGR %	-2.71	15.91	-4.45	-10.24	15.99
Accounts Receivable, 3 Yr. CAGR %	10.13	-30.11	-88.6	60.34	372.31
Net Property, Plant and Equip., 3 Yr. CAGR %	93.94	98.5	-15.7	-30.54	23.25
Total Assets, 3 Yr. CAGR %	25.61	35.59	16.97	3.33	28.9
Tangible Book Value, 3 Yr. CAGR %	32.34	38.67	39.18	6.39	31.05
Common Equity, 3 Yr. CAGR %	32.34	38.67	39.18	6.39	31.05
Cash From Operations, 3 Yr. CAGR %	165.52	29.26	37.58	-1.04	19.52
Capital Expenditures, 3 Yr. CAGR %	-10.91	31.34	-6.32	8.94	7.16
Levered Free Cash Flow, 3 Yr. CAGR %	15.71	17.92	18.62	22.75	1.87
Unlevered Free Cash Flow, 3 Yr. CAGR %	15.36	17.92	18.73	23.41	1.87
Compound Annual Growth Rate Over Five Years
Total Revenues, 5 Yr. CAGR %	-	-	5.79	14.17	351.71
Gross Profit, 5 Yr. CAGR %	-	-	5.79	14.17	351.71
EBITDA, 5 Yr. CAGR %	34.37	31.05	28.3	17.29	26.03
EBITA, 5 Yr. CAGR %	34.25	30.96	28.23	17.25	25.72
EBIT, 5 Yr. CAGR %	34.25	30.96	28.23	17.25	25.72
Earnings From Cont. Operations, 5 Yr. CAGR %	34.81	27.56	28.08	15.19	28.95
Net Income, 5 Yr. CAGR %	34.81	27.56	28.08	15.19	28.95
Normalized Net Income, 5 Yr. CAGR %	34.03	27.56	28.08	14.73	29.11
Diluted EPS Before Extra, 5 Yr. CAGR %	-49.63	-14.13	4.48	-4.38	7.25
Accounts Receivable, 5 Yr. CAGR %	-	-	-64.67	16.87	89.48
Net Property, Plant and Equip., 5 Yr. CAGR %	60.13	64.33	39.39	20.07	10.3
Total Assets, 5 Yr. CAGR %	85.32	29.9	8.65	20.74	36.89
Tangible Book Value, 5 Yr. CAGR %	59.13	27.93	12.32	24.51	53.22
Common Equity, 5 Yr. CAGR %	59.13	27.93	12.32	24.51	53.22
Cash From Operations, 5 Yr. CAGR %	38.19	29.19	94.63	7.06	34.7
Capital Expenditures, 5 Yr. CAGR %	3.37	25.98	3.6	4.62	6.98
Levered Free Cash Flow, 5 Yr. CAGR %	20.5	27.37	31.91	2.89	12.47
Unlevered Free Cash Flow, 5 Yr. CAGR %	20.28	27.37	31.91	2.89	12.54