Valuation: Protagonist Therapeutics, Inc.

Capitalization 5.96B 5.08B 4.74B 4.46B 8.22B 540B 8.98B 55.37B 21.48B 254B 22.37B 21.89B 929B P/E ratio 2025 *
-59.8x
P/E ratio 2026 * 95.7x
Enterprise value 5.77B 4.92B 4.59B 4.32B 7.96B 523B 8.69B 53.62B 20.8B 246B 21.66B 21.2B 899B EV / Sales 2025 *
86.4x
EV / Sales 2026 * 20.5x
Free-Float
95.31%
Yield 2025 *
-
Yield 2026 * -
More valuation ratios * Estimated data
Dynamic Chart
1 day+3.36%
1 week+6.36%
Current month+5.94%
1 month+12.37%
3 months+61.99%
6 months+69.30%
Current year+147.02%
More quotes
1 week 88.3
Extreme 88.3
95.39
1 month 82.06
Extreme 82.06
95.39
Current year 33.7
Extreme 33.7
95.39
1 year 33.7
Extreme 33.7
95.39
3 years 8.4
Extreme 8.4
95.39
5 years 6.91
Extreme 6.91
95.39
10 years 4.47
Extreme 4.47
95.39
More quotes
Manager TitleAgeSince
Chief Executive Officer 68 2008-11-30
Director of Finance/CFO 51 2022-04-17
Chief Tech/Sci/R&D Officer - 2025-01-01
Director TitleAgeSince
Director/Board Member 68 2008-11-30
Chairman 70 2014-03-18
Director/Board Member 68 2016-06-30
More insiders
Change 5d. change 1-year change 3-years change Capi.($)
+3.36%+6.36%+136.13%+1,119.31% 5.96B
-1.79%-5.23%-6.09%+11.09% 45.43B
-1.65%-1.59%+10.92%+4.28% 37.85B
-0.55%-1.19%+76.99%+56.17% 35.31B
+0.05%+1.91%+10.32%+20.20% 27.66B
-1.46%+1.78%+60.58%+164.03% 15.72B
+0.52%-0.90%+75.65%+231.60% 15.26B
-1.76%+0.38%-11.49%-5.32% 14.25B
-4.40%-7.89%+68.16% - 12.56B
+4.88%+7.29%+68.72%+79.89% 13.47B
Average -0.05%-0.11%+48.99%+186.81% 22.35B
Weighted average by Cap. -0.64%-1.29%+34.35%+80.57%
See all sector performances

Financials

2025 *2026 *
Net sales 66.81M 56.91M 53.16M 50.02M 92.09M 6.05B 101M 621M 241M 2.85B 251M 245M 10.41B 273M 233M 218M 205M 377M 24.77B 412M 2.54B 985M 11.68B 1.03B 1B 42.6B
Net income -102M -86.96M -81.23M -76.43M -141M -9.25B -154M -948M -368M -4.36B -383M -375M -15.9B 29.94M 25.51M 23.83M 22.42M 41.27M 2.71B 45.09M 278M 108M 1.28B 112M 110M 4.66B
Net Debt -188M -161M -150M -141M -260M -17.07B -284M -1.75B -679M -8.05B -707M -692M -29.36B -353M -301M -281M -264M -487M -31.98B -532M -3.28B -1.27B -15.07B -1.32B -1.3B -55B
More financial data * Estimated data
Logo Protagonist Therapeutics, Inc.
Protagonist Therapeutics, Inc. is a biopharmaceutical company. The Company uses its peptide-based chemical entities rusfertide and JNJ-2113 in different stages of development, all derived from its proprietary discovery technology platform. The Company’s clinical programs fall into two categories of diseases: hematology and blood disorders, and inflammatory and immunomodulatory diseases. Its lead clinical asset, rusfertide (PTG-300), is an injectable hepcidin mimetic in development for the potential treatment of polycythemia vera (PV) and other blood disorders. The Company’s Interleukin-23 receptor (IL-23R) antagonist compound JNJ-2113 is an orally delivered investigational drug that is designed to block biological pathways targeted by marketed injectable antibody drugs. Its PN-943 is a wholly owned investigational orally delivered gut-restricted alpha 4 beta 7 (α4β7) specific integrin antagonist for inflammatory bowel disease (IBD).
Employees
128
More about the company
Date Price Change Volume
25-12-12 95.35 $ +3.36% 1,287,130
25-12-11 92.25 $ +0.95% 800,761
25-12-10 91.38 $ +3.18% 1,308,400
25-12-09 88.56 $ -1.87% 1,440,173
25-12-08 90.25 $ +0.67% 1,455,768

Delayed Quote Nasdaq, December 12, 2025 at 04:00 pm

More quotes
Trader
Investor
Global
Quality
ESG MSCI
BB
More Ratings
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
12
Last Close Price
95.35USD
Average target price
92.83USD
Spread / Average Target
-2.64%
Consensus

Quarterly revenue - Rate of surprise