Balance Sheet Ionis Pharmaceuticals, Inc.

Equities

IONS

US4622221004

Biotechnology & Medical Research

Real-time Estimate Cboe BZX Other stock markets 10:04:00 2025-07-08 EDT			5-day change	1st Jan Change
42.00 ^USD	+0.54%		+4.46%	+19.34%

07-01	Ionis Pharmaceuticals Shares Rise After Barclays Upgrade	MT
07-01	All-Time Highs, All-Time Uncertainty

46533842708c87964.sI6qw8JMLNDFybCHtYzg-cPHYxX2mR_0zpIfgsMTSDM.59vNlKE7fbeBmObL88e1iLWLLV6-0W63_ft5tpRCG1bIy9ispgRkiYqqgA

Published financial data: IONIS PHARMACEUTICALS, INC.

Annual

Quarterly

Halfyear

YTD

LTM

Fiscal Period: December	2020	2021	2022	2023	2024
Revenues	729M	810M	587M	788M	705M
Total Revenues	729M	810M	587M	788M	705M
Cost of Goods Sold, Total	537M	643M	847M	909M	913M
Gross Profit	192M	167M	-260M	-121M	-208M
Selling General & Admin Expenses, Total	335M	171M	150M	213M	267M
Other Operating Expenses, Total	335M	171M	150M	213M	267M
Operating Income	-142M	-3.58M	-410M	-334M	-475M
Interest Expense, Total	-44.99M	-9.35M	-8.12M	-81.46M	-90.45M
Interest And Investment Income	30.56M	10.04M	25.33M	89.04M	107M
Net Interest Expenses	-14.43M	695K	17.21M	7.58M	16.57M
Other Non Operating Income (Expenses)	-62K	-1.13M	426K	867K	1.34M
EBT, Excl. Unusual Items	-157M	-4.02M	-393M	-325M	-457M
Restructuring Charges	-12.5M	-12.2M	-	-	-
Merger & Related Restructuring Charges	-15.3M	-11.7M	-	-	-
Gain (Loss) On Sale Of Investments	16.54M	10.1M	-7.33M	-1.91M	-2.89M
Gain (Loss) On Sale Of Assets	-	-	150M	-161K	-12K
Asset Writedown	-1.95M	-2.71M	-	-	-
Legal Settlements	-	-	-7.7M	-	-
Other Unusual Items	-	-8.63M	-	-6.61M	-
EBT, Incl. Unusual Items	-170M	-29.15M	-258M	-334M	-460M
Income Tax Expense	317M	-551K	11.74M	32.32M	-6.17M
Earnings From Continuing Operations	-487M	-28.6M	-270M	-366M	-454M
Net Income to Company	-487M	-28.6M	-270M	-366M	-454M
Minority Interest	35.48M	-	-	-	-
Net Income - (IS)	-451M	-28.6M	-270M	-366M	-454M
Preferred Dividend and Other Adjustments	201K	-	-	-	-
Net Income to Common Incl Extra Items	-451M	-28.6M	-270M	-366M	-454M
Net Income to Common Excl. Extra Items	-451M	-28.6M	-270M	-366M	-454M
Per Share Items
Net EPS - Basic	-3.23	-0.2	-1.9	-2.56	-3.04
Basic EPS - Continuing Operations	-3.23	-0.2	-1.9	-2.56	-3.04
Basic Weighted Average Shares Outstanding	140M	141M	142M	143M	150M
Net EPS - Diluted	-3.23	-0.2	-1.9	-2.56	-3.04
Diluted EPS - Continuing Operations	-3.23	-0.2	-1.9	-2.56	-3.04
Diluted Weighted Average Shares Outstanding	140M	141M	142M	143M	150M
Normalized Basic EPS	-0.45	-0.02	-1.73	-1.42	-1.91
Normalized Diluted EPS	-0.45	-0.02	-1.73	-1.42	-1.91
Supplemental Items
EBITDA	-127M	14.26M	-393M	-321M	-463M
EBITA	-140M	-1.23M	-408M	-334M	-475M
EBIT	-142M	-3.58M	-410M	-334M	-475M
EBITDAR	-117M	27.36M	-374M	-292M	-435M
Total Revenues (As Reported)	729M	810M	587M	788M	705M
Effective Tax Rate - (Ratio)	-186.28	1.89	-4.55	-9.68	1.34
Current Domestic Taxes	2.94M	-890K	11.65M	32.17M	-6.34M
Current Foreign Taxes	518K	339K	86K	147K	169K
Total Current Taxes	3.46M	-551K	11.74M	32.32M	-6.17M
Deferred Domestic Taxes	313M	-	-	-	-
Total Deferred Taxes	313M	-	-	-	-
Normalized Net Income	-62.54M	-2.51M	-245M	-203M	-286M
Interest on Long-Term Debt	44.99M	9.35M	8.12M	12.66M	16.99M
Supplemental Operating Expense Items
General and Administrative Expenses	-	-	-	-	-
Research And Development Expense From Footnotes	468M	584M	729M	803M	802M
Net Rental Expense, Total	10.2M	13.1M	19.2M	28.7M	28.5M
Imputed Operating Lease Interest Expense	4.51M	894K	952K	11.21M	10.51M
Imputed Operating Lease Depreciation	5.69M	12.21M	18.25M	17.49M	17.99M
Stock-Based Comp., COGS (Total)	-	87.98M	74.24M	78.32M	93.17M
Stock-Based Comp., G&A Exp. (Total)	-	-	-	-	-
Stock-Based Comp., SG&A Exp. (Total)	-	32.7M	26.03M	27.48M	37.03M
Stock-Based Comp., Other (Total)	230M	-	-	-	-
Total Stock-Based Compensation	230M	121M	100M	106M	130M

Fiscal Period: December	2020	2021	2022	2023	2024
Assets
Cash And Equivalents	398M	869M	276M	399M	242M
Short Term Investments	1.5B	1.28B	1.72B	1.94B	2.06B
Total Cash And Short Term Investments	1.9B	2.15B	2B	2.34B	2.3B
Accounts Receivable, Total	76.2M	61.9M	25.54M	97.78M	92.19M
Total Receivables	76.2M	61.9M	25.54M	97.78M	92.19M
Inventory	21.96M	24.81M	22.03M	28.42M	12.51M
Other Current Assets, Total	133M	113M	158M	178M	213M
Total Current Assets	2.13B	2.35B	2.2B	2.64B	2.62B
Gross Property Plant And Equipment	282M	299M	344M	340M	362M
Accumulated Depreciation	-87.38M	-103M	-87.72M	-96.76M	-106M
Net Property Plant And Equipment	194M	196M	256M	243M	256M
Long-term Investments	15.06M	15.62M	40.37M	42.99M	41.02M
Other Intangibles, Total	27.94M	29M	-	-	-
Deferred Tax Assets Long-Term	-	-	-	-	-
Other Long-Term Assets, Total	21.87M	25.95M	34.97M	62.29M	86.26M
Total Assets	2.39B	2.61B	2.53B	2.99B	3B
Liabilities
Accounts Payable, Total	17.2M	11.9M	17.92M	26.03M	42.96M
Accrued Expenses, Total	156M	127M	189M	216M	178M
Current Portion of Long-Term Debt	298M	926K	320K	45.07M	215K
Current Portion of Leases	2M	2.6M	7.22M	8.09M	9.06M
Current Income Taxes Payable	1.32M	36K	6.25M	2.15M	34K
Unearned Revenue Current, Total	108M	97.71M	90.58M	151M	78.99M
Total Current Liabilities	583M	241M	312M	448M	309M
Long-Term Debt	524M	1.23B	1.18B	1.74B	1.79B
Long-Term Leases	15.31M	19.46M	179M	171M	162M
Unearned Revenue Non Current	424M	352M	288M	241M	157M
Total Liabilities	1.55B	1.84B	1.96B	2.6B	2.42B
Common Stock, Total	140K	141K	142K	144K	158K
Additional Paid In Capital	2.11B	1.96B	2.06B	2.22B	2.87B
Retained Earnings	-1.25B	-1.16B	-1.43B	-1.8B	-2.25B
Comprehensive Income and Other	-21.07M	-32.67M	-57.48M	-32.64M	-30.81M
Total Common Equity	843M	772M	573M	387M	588M
Minority Interest	-	-	-	-	-
Total Equity	843M	772M	573M	387M	588M
Total Liabilities And Equity	2.39B	2.61B	2.53B	2.99B	3B
Supplemental Items
ECS Total Shares Outstanding on Filing Date	141M	142M	143M	146M	159M
ECS Total Common Shares Outstanding	140M	141M	142M	144M	158M
Book Value / Share	6.01	5.47	4.03	2.68	3.73
Tangible Book Value	815M	743M	573M	387M	588M
Tangible Book Value Per Share	5.81	5.26	4.03	2.68	3.73
Total Debt	840M	1.25B	1.37B	1.97B	1.96B
Net Debt	-1.06B	-894M	-628M	-370M	-344M
Debt Equivalent Oper. Leases	81.6M	105M	154M	230M	228M
Minority Interest, Total (Incl. Fin. Div)	-	-	-	-	-
Account Code - Inventory Valuation	5	5	5	5	5
Inventories - Raw Materials, Total	16.71M	18.65M	19.76M	22.79M	5.56M
Inventories - Work In Process, Total	2.25M	5.77M	2.11M	5.48M	6.68M
Inventories - Finished Goods, Total	3M	390K	164K	154K	276K
Land - (BS)	23.06M	23.06M	8.57M	8.57M	8.57M
Buildings, Total	138M	144M	41.16M	41.23M	41.23M
Machinery, Total	12.87M	10.59M	9.58M	9.84M	9.86M
Full Time Employees	757	660	796	927	1.07K

Fiscal Period: December	2020	2021	2022	2023	2024
Net Income	-451M	-28.6M	-270M	-366M	-454M
Depreciation & Amortization - CF	15.1M	17.21M	19.69M	22.5M	21.99M
Amortization of Goodwill and Intangible Assets - (CF)	2.06M	2.35M	2.42M	-	-
Depreciation & Amortization, Total	17.16M	19.56M	22.1M	22.5M	21.99M
Amortization of Deferred Charges, Total - (CF)	38.74M	4.96M	5.37M	6.33M	6.69M
(Gain) Loss From Sale Of Asset	-	-	-148M	18.47M	10.44M
(Gain) Loss on Sale of Investments - (CF)	-5.02M	16.68M	7.61M	-27.3M	-34.84M
Asset Writedown & Restructuring Costs	1.95M	2.71M	-	-	-
Stock-Based Compensation (CF)	230M	121M	100M	106M	130M
Other Operating Activities, Total	278M	8.63M	-	10.22M	27.86M
Change In Accounts Receivable	-13.17M	14.31M	36.36M	-72.06M	5.59M
Change In Inventories	-1.26M	-2.84M	2.77M	-6.39M	-5.07M
Change In Accounts Payable	-2.76M	-6M	1.09M	8.12M	15.99M
Change in Unearned Revenues	-75.91M	-82.83M	-71.25M	13.97M	-157M
Change In Income Taxes	-31.28M	-280K	6.21M	-4.1M	-2.12M
Change in Other Net Operating Assets	50.82M	-36.18M	32.38M	-16.8M	-66.96M
Cash from Operations	35.89M	30.8M	-274M	-308M	-501M
Capital Expenditure	-35.12M	-11.96M	-15.72M	-23.8M	-45.28M
Sale (Purchase) of Real Estate properties	-	-	254M	22K	-
Sale (Purchase) of Intangible assets	-5.93M	-5.95M	-4.38M	-4.21M	-5.06M
Investment in Marketable and Equity Securities, Total	316M	213M	-497M	-186M	-83.69M
Cash from Investing	274M	195M	-263M	-214M	-134M
Long-Term Debt Issued, Total	-	632M	-	575M	-
Total Debt Issued	-	632M	-	575M	-
Long-Term Debt Repaid, Total	-	-319M	-50.69M	-488M	-44.67M
Total Debt Repaid	-	-319M	-50.69M	-488M	-44.67M
Issuance of Common Stock	52.04M	11.56M	6.37M	49.44M	523M
Repurchase of Common Stock	-104M	-16.72M	-10.95M	-	-
Other Financing Activities, Total	-545M	-62.48M	-29K	508M	-
Cash from Financing	-597M	246M	-55.3M	644M	478M
Foreign Exchange Rate Adjustments	617K	-111K	-418K	352K	-273K
Net Change in Cash	-286M	472M	-593M	123M	-157M
Supplemental Items
Cash Interest Paid	6.25M	4.78M	2.9M	6.51M	10.87M
Cash Income Tax Paid (Refund)	25.86M	38K	5.01M	48.33M	-5.62M
Levered Free Cash Flow	120M	105M	-80.22M	-161M	-353M
Unlevered Free Cash Flow	109M	106M	-80.51M	-116M	-303M
Change In Net Working Capital	7.94M	14.15M	-73.59M	8.16M	108M
Net Debt Issued / Repaid	-	314M	-50.69M	86.9M	-44.67M

Fiscal Period: December	2020	2021	2022	2023	2024
Profitability
Return on Assets	-3.16	-0.09	-9.96	-7.55	-9.91
Return on Total Capital	-4.28	-0.12	-12.93	-9.71	-12.12
Return On Equity %	-38.51	-3.78	-40.12	-76.34	-93.1
Return on Common Equity	-39.01	-3.78	-40.12	-76.34	-93.1
Margin Analysis
Gross Profit Margin %	26.37	20.65	-44.25	-15.38	-29.44
SG&A Margin	45.88	21.09	25.59	26.99	37.93
EBITDA Margin %	-17.4	1.76	-66.98	-40.74	-65.68
EBITA Margin %	-19.23	-0.15	-69.42	-42.37	-67.37
EBIT Margin %	-19.52	-0.44	-69.84	-42.37	-67.37
Income From Continuing Operations Margin %	-66.75	-3.53	-45.92	-46.5	-64.37
Net Income Margin %	-61.88	-3.53	-45.92	-46.5	-64.37
Net Avail. For Common Margin %	-61.91	-3.53	-45.92	-46.5	-64.37
Normalized Net Income Margin	-8.58	-0.31	-41.77	-25.81	-40.52
Levered Free Cash Flow Margin	16.45	12.96	-13.66	-20.44	-50.04
Unlevered Free Cash Flow Margin	14.99	13.07	-13.71	-14.78	-42.97
Asset Turnover
Asset Turnover	0.26	0.32	0.23	0.29	0.24
Fixed Assets Turnover	4.19	4.3	2.6	3.16	2.83
Receivables Turnover (Average Receivables)	10.48	11.74	13.44	12.77	7.42
Inventory Turnover (Average Inventory)	26.75	27.5	36.18	36.02	91.49
Short Term Liquidity
Current Ratio	3.65	9.75	7.07	5.9	8.47
Quick Ratio	3.39	9.17	6.49	5.43	7.74
Operating Cash Flow to Current Liabilities	0.06	0.13	-0.88	-0.69	-1.62
Days Sales Outstanding (Average Receivables)	34.94	31.1	27.17	28.57	49.3
Days Outstanding Inventory (Average Inventory)	13.68	13.27	10.09	10.13	4
Average Days Payable Outstanding	11.26	8.22	6.45	8.76	13.76
Cash Conversion Cycle (Average Days)	37.36	36.15	30.81	29.94	39.55
Long Term Solvency
Total Debt/Equity	99.55	162.11	239	508.75	332.93
Total Debt / Total Capital	49.89	61.85	70.5	83.57	76.9
LT Debt/Equity	63.93	161.65	237.68	495	331.35
Long-Term Debt / Total Capital	32.03	61.67	70.11	81.31	76.54
Total Liabilities / Total Assets	64.71	70.45	77.39	87.07	80.41
EBIT / Interest Expense	-3.16	-0.38	-50.5	-4.1	-5.25
EBITDA / Interest Expense	-2.59	2.93	-46.08	-3.59	-4.81
(EBITDA - Capex) / Interest Expense	-3.37	1.65	-48.01	-3.88	-5.31
Total Debt / EBITDA	-7.19	45.73	-3.66	-6.73	-4.51
Net Debt / EBITDA	9.08	-32.68	1.68	1.27	0.79
Total Debt / (EBITDA - Capex)	-5.53	81.21	-3.51	-6.23	-4.08
Net Debt / (EBITDA - Capex)	6.98	-58.03	1.61	1.17	0.72
Growth Over Prior Year
Total Revenues, 1 Yr. Growth %	-35.04	11.13	-27.53	34.1	-10.48
Gross Profit, 1 Yr. Growth %	-70.63	-13	-257.84	-53.4	71.42
EBITDA, 1 Yr. Growth %	-133.17	-117.3	-3.51K	-18.44	44.33
EBITA, 1 Yr. Growth %	-137.91	-98.72	10.27K	-18.64	42.35
EBIT, 1 Yr. Growth %	-138.67	-96.34	6.43K	-18.64	42.35
Earnings From Cont. Operations, 1 Yr. Growth %	-260.51	-94.04	843.18	35.8	23.92
Net Income, 1 Yr. Growth %	-253.42	-93.56	843.18	35.8	23.92
Normalized Net Income, 1 Yr. Growth %	-128.1	-79.99	5.74K	-18.73	40.55
Diluted EPS Before Extra, 1 Yr. Growth %	-255.47	-93.63	837.69	34.53	18.68
Accounts Receivable, 1 Yr. Growth %	20.89	-18.78	-58.74	282.87	-5.72
Inventory, 1 Yr. Growth %	20.82	12.93	-11.18	29.01	68.15
Net Property, Plant and Equip., 1 Yr. Growth %	26.38	8.28	30.5	-5.04	5.42
Total Assets, 1 Yr. Growth %	-26.08	9.29	-2.98	18	0.45
Tangible Book Value, 1 Yr. Growth %	-43.59	3.83	-25.77	-32.5	52.15
Common Equity, 1 Yr. Growth %	-42.67	3.83	-25.77	-32.5	52.15
Cash From Operations, 1 Yr. Growth %	-89.62	-14.19	-990.84	12.08	62.9
Capital Expenditures, 1 Yr. Growth %	13.64	-65.96	31.5	51.42	90.21
Levered Free Cash Flow, 1 Yr. Growth %	-57.01	-21.85	-187.69	100.75	119.11
Unlevered Free Cash Flow, 1 Yr. Growth %	-59.54	-22.74	-187.17	44.64	160.19
Compound Annual Growth Rate Over Two Years
Total Revenues, 2 Yr. CAGR %	10.28	-15.03	-10.25	-1.42	9.57
Gross Profit, 2 Yr. CAGR %	2.21	-49.44	-39.81	-11.93	-10.62
EBITDA, 2 Yr. CAGR %	62.53	-80.69	58.48	409.79	8.49
EBITA, 2 Yr. CAGR %	54.52	-94.24	54.87	232.5	7.62
EBIT, 2 Yr. CAGR %	53.29	-90.14	54.39	232.5	7.62
Earnings From Cont. Operations, 2 Yr. CAGR %	50.47	-68.45	-25.02	257.89	29.72
Net Income, 2 Yr. CAGR %	28.4	-67.94	-22.08	257.89	29.72
Normalized Net Income, 2 Yr. CAGR %	130.3	-89.88	104	225.91	6.87
Diluted EPS Before Extra, 2 Yr. CAGR %	24.99	-67.33	-22.7	255.17	26.35
Accounts Receivable, 2 Yr. CAGR %	144.39	-0.91	-42.11	25.69	90
Inventory, 2 Yr. CAGR %	59.98	16.81	0.15	7.05	-24.64
Net Property, Plant and Equip., 2 Yr. CAGR %	21.21	12.96	18.86	11.32	0.05
Total Assets, 2 Yr. CAGR %	-5.35	-10.12	2.97	7	8.88
Tangible Book Value, 2 Yr. CAGR %	-10.77	-28.32	-10.51	-29.21	1.34
Common Equity, 2 Yr. CAGR %	-10.3	-27.57	-12.21	-29.21	1.34
Cash From Operations, 2 Yr. CAGR %	-75.6	-70.15	176.48	215.98	35.12
Capital Expenditures, 2 Yr. CAGR %	60.65	-37.8	-33.09	41.11	69.71
Levered Free Cash Flow, 2 Yr. CAGR %	-9	-37.08	-4.55	45.05	109.73
Unlevered Free Cash Flow, 2 Yr. CAGR %	-10.88	-37.38	-5.8	22.64	93.99
Compound Annual Growth Rate Over Three Years
Total Revenues, 3 Yr. CAGR %	12.35	10.56	-19.42	2.6	-4.53
Gross Profit, 3 Yr. CAGR %	11.18	-3.12	-26.51	-44.73	9.96
EBITDA, 3 Yr. CAGR %	47.19	-33.29	0.94	27	234.74
EBITA, 3 Yr. CAGR %	61.84	-72.46	3.29	25.21	150.6
EBIT, 3 Yr. CAGR %	65.42	-61.05	3.67	24.71	150.6
Earnings From Cont. Operations, 3 Yr. CAGR %	256.06	-48.95	-2.08	-8.6	151.31
Net Income, 3 Yr. CAGR %	992.59	-52.9	-1.02	-6.23	151.31
Normalized Net Income, 3 Yr. CAGR %	122.1	-40.29	0.01	51.08	146.23
Diluted EPS Before Extra, 3 Yr. CAGR %	178.32	-53.9	0.03	-7.02	146.46
Accounts Receivable, 3 Yr. CAGR %	6.57	69.28	-26	8.66	14.2
Inventory, 3 Yr. CAGR %	30.07	42.45	6.62	8.97	-20.4
Net Property, Plant and Equip., 3 Yr. CAGR %	16.79	14.05	18.52	10.29	9.32
Total Assets, 3 Yr. CAGR %	21.79	-0.71	-7.8	7.76	4.77
Tangible Book Value, 3 Yr. CAGR %	46.56	-10.15	-26.54	-18.54	-8.65
Common Equity, 3 Yr. CAGR %	44.24	-9.7	-26.97	-19.57	-8.65
Cash From Operations, 3 Yr. CAGR %	-40.93	-62.9	-7.41	104.62	153.37
Capital Expenditures, 3 Yr. CAGR %	0.34	-4.23	-20.17	-12.16	55.88
Levered Free Cash Flow, 3 Yr. CAGR %	-12.13	-10.15	-32.89	22.29	66.43
Unlevered Free Cash Flow, 3 Yr. CAGR %	-14.05	-8.36	-33.21	8.67	57.58
Compound Annual Growth Rate Over Five Years
Total Revenues, 5 Yr. CAGR %	20.78	16.8	2.7	5.6	-8.88
Gross Profit, 5 Yr. CAGR %	38.68	40.33	13.18	-8.03	-20.52
EBITDA, 5 Yr. CAGR %	14.52	10.07	58.13	46.2	3.9
EBITA, 5 Yr. CAGR %	14.46	-40.39	65.25	41.54	5.13
EBIT, 5 Yr. CAGR %	13.77	-27.49	67.14	40.68	5.23
Earnings From Cont. Operations, 5 Yr. CAGR %	40.7	-13.89	90.39	11.25	9.58
Net Income, 5 Yr. CAGR %	38.59	-13.89	278.76	6	10.29
Normalized Net Income, 5 Yr. CAGR %	-1.34	-39.89	112.16	76.73	3.1
Diluted EPS Before Extra, 5 Yr. CAGR %	34.31	-16.51	66.19	4.32	9.83
Accounts Receivable, 5 Yr. CAGR %	46.34	-10.54	-16.51	50.27	7.9
Inventory, 5 Yr. CAGR %	26.06	27.07	17.16	27.06	-7.2
Net Property, Plant and Equip., 5 Yr. CAGR %	16.56	16.13	15.98	12.95	10.76
Total Assets, 5 Yr. CAGR %	20.31	23.41	13.88	2.31	-1.46
Tangible Book Value, 5 Yr. CAGR %	35.06	56.47	17.21	-17.7	-16.45
Common Equity, 5 Yr. CAGR %	33.25	50.62	15.31	-18.08	-16.75
Cash From Operations, 5 Yr. CAGR %	11.18	-22.77	9.52	-12.6	7.71
Capital Expenditures, 5 Yr. CAGR %	35.49	10.96	-14.68	11.83	7.94
Levered Free Cash Flow, 5 Yr. CAGR %	30.54	17.15	-14.62	2.14	5.86
Unlevered Free Cash Flow, 5 Yr. CAGR %	28.34	16.93	-14.11	-3.29	2.32